Tadashi Matsuda Selected Research

Cytokines

7/2021	Propolis suppresses cytokine production in activated basophils and basophil-mediated skin and intestinal allergic inflammation in mice.
1/2020	Dimethyl fumarate dampens IL-17-ACT1-TBK1 axis-mediated phosphorylation of Regnase-1 and suppresses IL-17-induced IκB-ζ expression.
10/2017	Successful maintenance of key physiological parameters in preterm lambs treated with ex vivo uterine environment therapy for a period of 1 week.
1/2017	DNA-Containing Exosomes Derived from Cancer Cells Treated with Topotecan Activate a STING-Dependent Pathway and Reinforce Antitumor Immunity.
1/2016	IL-17A plays a central role in the expression of psoriasis signature genes through the induction of IκB-ζ in keratinocytes.
5/2014	Tyk2 is a therapeutic target for psoriasis-like skin inflammation.
9/2011	Tyk2 deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice.
11/2009	A single polymorphic amino acid on Toxoplasma gondii kinase ROP16 determines the direct and strain-specific activation of Stat3.

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Tadashi Matsuda Research Topics

Disease

40	Neoplasms (Cancer) 01/2024 - 03/2002
25	Prostatic Neoplasms (Prostate Cancer) 01/2024 - 02/2002
13	Carcinoma (Carcinomatosis) 07/2022 - 01/2003
12	Urinary Bladder Neoplasms (Bladder Cancer) 03/2021 - 03/2002
12	Hemorrhage 09/2018 - 05/2002
11	Inflammation (Inflammations) 07/2021 - 07/2011
10	Neoplasm Metastasis (Metastasis) 03/2024 - 07/2003
9	Breast Neoplasms (Breast Cancer) 01/2024 - 07/2002
7	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 05/2023 - 01/2002
6	Renal Cell Carcinoma (Grawitz Tumor) 03/2020 - 08/2012
6	Hypogonadism (Hypergonadotropic Hypogonadism) 01/2018 - 09/2007
6	Lower Urinary Tract Symptoms 11/2017 - 05/2015
6	Infections 10/2017 - 11/2004
5	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2020 - 07/2011
5	Pain (Aches) 01/2019 - 10/2010
4	Autoimmune Diseases (Autoimmune Disease) 11/2022 - 01/2017
4	Urolithiasis 01/2021 - 09/2017
4	Pheochromocytoma 12/2019 - 01/2009
4	Lymphoma (Lymphomas) 07/2015 - 01/2006
4	Hepatocellular Carcinoma (Hepatoma) 05/2015 - 01/2003
3	Melanoma (Melanoma, Malignant) 03/2024 - 07/2015
3	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 02/2024 - 12/2016
3	Lung Neoplasms (Lung Cancer) 01/2024 - 07/2003
3	Hyperplasia 05/2023 - 05/2014
3	Overactive Urinary Bladder (Overactive Bladder) 01/2022 - 08/2017
3	Urinary Tract Infections (Urinary Tract Infection) 11/2021 - 09/2006
3	Carcinogenesis 01/2021 - 07/2015
3	Tyrosine Kinase 2 Deficiency 03/2020 - 09/2011
3	Paraganglioma (Paragangliomas) 12/2019 - 01/2009
3	Arthritis (Polyarthritis) 01/2017 - 09/2011
3	Urinary Retention 08/2016 - 04/2011
3	Fever (Fevers) 02/2014 - 06/2005
3	Leukemia 07/2008 - 07/2003
2	Hypersensitivity (Allergy) 11/2022 - 07/2021
2	Bites and Stings (Sting) 01/2022 - 01/2017
2	Adenocarcinoma 09/2021 - 09/2007
2	Anaphylaxis (Anaphylactic Shock) 07/2021 - 04/2014
2	Pyuria 11/2020 - 01/2020
2	Wounds and Injuries (Trauma) 01/2020 - 01/2020
2	Margins of Excision 01/2020 - 06/2012

Drug/Important Bio-Agent (IBA)

17	Proteins (Proteins, Gene)FDA Link 01/2024 - 07/2002
8	Phosphotransferases (Kinase)IBA 01/2024 - 07/2003
8	Messenger RNA (mRNA)IBA 01/2022 - 02/2002
8	CytokinesIBA 07/2021 - 11/2009
8	AndrogensIBA 01/2019 - 01/2004
7	Interleukin-17 (Interleukin 17)IBA 01/2020 - 03/2012
5	Prostate-Specific Antigen (Semenogelase)IBA 08/2021 - 09/2007
5	Testosterone (Sustanon)FDA Link 01/2019 - 02/2009
5	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 12/2014 - 07/2005
4	Peptides (Polypeptides)IBA 01/2024 - 06/2005
4	Dutasteride (Avodart)FDA Link 05/2023 - 09/2015
3	ErbB Receptors (EGF Receptor)IBA 01/2024 - 11/2017
3	Immunoglobulin E (IgE)IBA 07/2021 - 01/2004
3	Hemoglobins (Hemoglobin)IBA 02/2019 - 04/2006
3	Chorionic Gonadotropin (Human Chorionic Gonadotropin)FDA LinkGeneric 09/2018 - 01/2018
3	Cisplatin (Platino)FDA LinkGeneric 09/2018 - 06/2013
3	LigandsIBA 01/2017 - 02/2007
3	DNA (Deoxyribonucleic Acid)IBA 01/2017 - 03/2002
3	IntegrinsIBA 01/2017 - 10/2004
3	Collagen Type II (Type II Collagen)IBA 01/2017 - 09/2011
3	EndotoxinsIBA 12/2014 - 12/2007
3	Small Interfering RNA (siRNA)IBA 05/2011 - 01/2006
3	Interleukin-6 (Interleukin 6)IBA 07/2008 - 01/2003
2	Monophenol Monooxygenase (Tyrosinase)IBA 03/2024 - 07/2015
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 11/2022 - 01/2022
2	9 alpha,11 alpha,15 alpha- trihydroxy- 16- phenoxy- 17,18,19,20- tetranorprosta- 4,5,13- trienoic acid (TPT)IBA 01/2022 - 01/2017
2	Topotecan (Hycamtin)FDA LinkGeneric 01/2022 - 01/2017
2	CateninsIBA 12/2021 - 05/2011
2	SynaptophysinIBA 09/2021 - 01/2010
2	Chromogranin AIBA 09/2021 - 01/2010
2	Eosine Yellowish-(YS) (Eosin)IBA 09/2021 - 03/2021
2	Hematoxylin (Haematoxylon)IBA 09/2021 - 03/2021
2	Interleukin-4 (Interleukin 4)IBA 07/2021 - 01/2004
2	AcidsIBA 06/2021 - 01/2020
2	Uroplakin IIIBA 03/2021 - 07/2003
2	Interleukin-10 (Interleukin 10)IBA 01/2021 - 03/2020
2	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2021 - 01/2003
2	InterferonsIBA 01/2021 - 09/2013
2	Concanavalin AIBA 01/2021 - 01/2020

Therapy/Procedure

24	Therapeutics 07/2022 - 06/2005
14	Prostatectomy (Retropubic Prostatectomy) 05/2020 - 04/2003
12	Nephrectomy 11/2021 - 03/2002
10	Cystectomy 03/2017 - 03/2002
6	Drug Therapy (Chemotherapy) 01/2022 - 06/2005
6	Stents 01/2022 - 11/2017
4	Adrenalectomy 12/2021 - 01/2017
4	Operative Time 11/2021 - 06/2012
3	Nephroureterectomy 07/2022 - 03/2009
3	Lasers (Laser) 06/2021 - 01/2016
3	Lithotripsy (Extracorporeal Shockwave Lithotripsy) 01/2020 - 09/2017
3	Castration 02/2019 - 09/2008
3	Orchiectomy (Orchidectomy) 09/2018 - 12/2010
3	Conservative Treatment 02/2018 - 03/2011
3	Kidney Transplantation 10/2017 - 10/2015
3	Catheters 11/2016 - 06/2005
2	Laser Therapy (Surgery, Laser) 06/2021 - 01/2018
2	Urinary Catheters 01/2021 - 11/2011
2	Lymph Node Excision (Lymph Node Dissection) 01/2021 - 10/2019
2	Transurethral Resection of Bladder 11/2020 - 03/2011
2	Blood Transfusion (Blood Transfusions) 01/2020 - 02/2014